… tumor progression is closely associated with the formation of new vessels. Brain tumor
angiogenesis … mediates proteolysis of matrix components and enhances the synthesis of collagen, …

… To further explore the function of collagen genes in promoting glioma progression, we used
rarely studied COL3A1 as a further research object. The results showed that the knockdown …

… Collagen, as a matrix component, plays an essential role in … leading to angiogenesis. (33)
Thus, the development of spheroid … for every stage of tumor advancement. Therefore, this work …

… the ECM, GBM cells and EC in the tumor angiogenesis and … collagen subtypes (V, VI,
XXII, and XXVII) in EC from GBM. … to strongly impact tumor development and progression by …

… angiogenic process has such a significant role in GBM survival and progression, which
pushed the approval of anti-angiogenic … described GBM ECM composition, Matrigel, collagen, …

… These studies suggest that COL6A1 plays significant role in tumor progression. … and
expression of collagen inhibit tumor angiogenesis, but does not promote glioma invasion and …

… a novel role for TIMP1 in facilitating glioblastoma tumor cell … the role of angiocrine signals
in glioblastoma progression. … -angiogenic signaling to promote new capillary formation at the …

… In addition, collagen is upregulated during glioma … a critical role in glioblastoma progression
and tumour invasion, … has been shown to function as a mediator of neo-angiogenesis. In …

… has shown that collagen I contribute to glioma progression. It … increase collagen IV expression
and upregulate angiogenic … invasion through the collagen matrix.[ 49 ] G protein-coupled …

… in GBM progression. While in many aspects, the … with other ECM proteins such as collagens,
fibronectin, tenascin C, or … the RGD motif inhibited also tumor angiogenesis. Based on these …